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Levaquin
 
Product Detail
Generic Name Levofloxacin Average Delivery 10-12 days
Strenght(s) 500 mg
Brand Name Levaquin Shipping worldwide
 
DESCRIPTION

LEVAQUIN® is a synthetic broad-spectrum antibacterial agent for oral and intravenous administration. Chemically, levofloxacin, a chiral fluorinated carboxyquinolone, is the pure (-)-(S)-enantiomer of the racemic drug substance ofloxacin. The chemical name is (-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate.

Figure 1 : The Chemical Structure of Levofloxacin

Chemical Structure

The empirical formula is C18H20FN3O4 • ½ H2O and the molecular weight is 370.38. Levofloxacin is a light yellowish-white to yellow-white crystal or crystalline powder. The molecule exists as a zwitterion at the pH conditions in the small intestine.

The data demonstrate that from pH 0.6 to 5.8, the solubility of levofloxacin is essentially constant (approximately 100 mg/mL). Levofloxacin is considered soluble to freely soluble in this pH range, as defined by USP nomenclature. Above pH 5.8, the solubility increases rapidly to its maximum at pH 6.7 (272 mg/mL) and is considered freely soluble in this range. Above pH 6.7, the solubility decreases and reaches a minimum value (about 50 mg/mL) at a pH of approximately 6.9.

Levofloxacin has the potential to form stable coordination compounds with many metal ions. This in vitro chelation potential has the following formation order: Al+3>Cu+2>Zn+2>Mg+2>Ca+2.

Excipients and Description of Dosage Forms

LEVAQUIN® Tablets

LEVAQUIN® Tablets are available as film-coated tablets and contain the following inactive ingredients:

  • 250 mg (as expressed in the anhydrous form): crospovidone, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, synthetic red iron oxide and titanium dioxide.
  • 500 mg (as expressed in the anhydrous form): crospovidone, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, synthetic red and yellow iron oxides and titanium dioxide.
  • 750 mg (as expressed in the anhydrous form): crospovidone, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, titanium dioxide.
 
Quantity Dosage Old Price Price Shipping Add to cart
360 Pills 500 mg $ 0.00 $ 419.00 worldwide
180 pills 500 mg $ 0.00 $ 230.00 worldwide
120 pills 500 mg $ 0.00 $ 175.00 worldwide
90 pills 500 mg $ 0.00 $ 135.00 worldwide
60 pills 500 mg $ 0.00 $ 115.00 worldwide
360 Pills 500 mg $ 0.00 $ 399.00 worldwide
180 pills 250 mg $ 0.00 $ 210.00 worldwide
120 pills 250 mg $ 0.00 $ 155.00 worldwide
90 pills 250 mg $ 0.00 $ 115.00 worldwide
60 pills 250 mg $ 0.00 $ 89.00 worldwide
 

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